CIRC_0101692 KNOCKDOWN RETARDS THE DEVELOPMENT OF CLEAR CELL RENAL CELL CARCINOMA THROUGH MIR-384/FN1 PATHWAY

Circ_0101692 knockdown retards the development of clear cell renal cell carcinoma through miR-384/FN1 pathway

Purpose: Circular RNA_0101692 (circ_0101692) is overexpressed in clear cell renal cell carcinoma (ccRCC) by microarray analyses.However, its function and action mechanism in ccRCC tumorigenesis is still elusive.Methods: Western blotting and qRT-PCR were executed to assess the circ_0101692, miR-384 and FN1 expression in ccRCC cells and tissues.Targe

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Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing.

BACKGROUND: Fracture healing is orchestrated by a specific set of events that culminates in the repair of bone and reachievement of its biomechanical properties.The aim of our work was to study the sequence of gene expression events involved in inflammation and bone remodeling occurring in the early phases of callus formation in osteoporotic patien

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Effect of garlic extract, ascorbic acid and nicotinamide on growth, some biochemical aspects, yield and its components of three faba bean (Vicia faba L.) cultivars under sandy soil conditions

Abstract Background Garlic extract is a highly nutritive value extract; it contains large number of important enzymes and more than 200 biochemical compounds such as antioxidants and vitamins.Ascorbic acid and nicotinamide are considered as antioxidants and also known as growth-regulating compounds that influence different physiological and biochem

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NATURE-USE AND SUSTAINABLE DEVELOPMENT

The fundamental difference between a traditional economy and geoecological economy is discussed in the Makeup Sponges article.The deeper the economy is being introduced into the ecosystem, the stronger it will be pressure on it that is outside the ecosystem, the more destructive is this incompatibility.It is concluded that the geoecological sustain

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